• br Hematopoietic cell transplantation HCT is

  2019-06-29

  

  Hematopoietic cell transplantation HCT is generally recommended for AML patients with intermediate or high risk cytogenetics, when the aim of treatment is curative. However, elderly patients are seldom offered a transplant mainly due to concerns regarding toxicity, despite the fact that the main

• The coverage and quality of laboratory services throughout A

  2019-06-29

  

  The coverage and quality of laboratory services throughout Africa is inadequately documented. Quality provided by individual laboratories is questioned, and not all facilities are enrolled in external quality assurance schemes. For example, in 2013, an evaluation of accredited laboratories in sub-Sa

• br Introduction Incidence of oral cancers accounts for of al

  2019-06-29

  

  Introduction Incidence of oral cancers accounts for ∼3% of all malignancies. Oral squamous cell carcinoma (OSCC) accounts for >95% of all malignancies in the oral cavity, and it is the fifth leading cause of cancer death in the male population in Taiwan. OSCC is treated mainly with surgery. Post

• Previous studies have demonstrated localization of miR stain

  2019-06-29

  

  Previous studies have demonstrated localization of miR-21 staining in stromal CUDC-907 weight of OSCC associated with the tongue and mouth floor—this might be a useful prognostic predictor. We also observed miR-21 staining in the stromal cells of tumors. However, since multiple lines of evidence ind

• Atrial fibrillation is the most common atrial arrhythmia

  2019-06-28

  

  Atrial fibrillation is the most common atrial arrhythmia studied in BrS [3–14]. The prevalence of AF has been reported to be higher in patients with BrS than in the general Lovastatin of the same age [15,16]. Earlier studies reported an approximately 10–50% prevalence of spontaneous, clinical AF in

• In Telek Ayove and colleagues report a comparison of

  2019-06-28

  

  In , Telek Ayove and colleagues report a comparison of the Dual Path Platform (DPP) Syphilis Screen and Confirm test (Chembio Diagnostic Systems, Medford, NY, USA) with non-treponemal (RPR) and treponemal (TPHA) serological tests for diagnosis of yaws in two remote communities in Papua New Guinea wi

• As Canadians queue to vote in the federal election

  2019-06-28

  

  As Canadians queue to vote in the federal election next week, some will be uncomfortable knowing that the new Fair Elections Act that requires an official photo identification will overwhelmingly discriminate against those who are least likely to produce it—the very groups cited by UNCOHR. Many Cana

• br Clinical characteristics Brugada syndrome is more common

  2019-06-28

  

  Clinical characteristics Brugada syndrome is more common in Southeast Asia, including Japan, with an estimated prevalence of 12 in 10,000 individuals, compared with Western countries where the estimated prevalence is 1 to 5 in 10,000 individuals. However, the incidence of early repolarization syn

• Pyronaridine Tetraphosphate weight br The Editorial in about

  2019-06-28

  

  The Editorial in about global health inequity raises some important issues. The global health Pyronaridine Tetraphosphate weight long ago acknowledged the worldwide disparities in health, but it has failed to take action; most of the efforts have been made in reporting the disparities among specif

• In an early meta analysis diagnosing

  2019-06-28

  

  In an early meta-analysis, diagnosing cancer of the pancreas by ERCP with the “double duct” sign had a sensitivity of 92% and specificity of 96%. In the present case, mild proximal CBD dilatation with an abrupt distal CBD stricture was detected by ERCP. The most common malignant cause of obstructive

• Further complicating matters is that although menopause

  2019-06-28

  

  Further complicating matters is that although menopause can increase serum BTMs, other normal physiological conditions, certain disease states, and drugs are also associated with elevated BTM concentrations [81–83]. Low body-mass index (BMI) is a risk factor for low bone density [84] and evidence ha

• Based on these preliminary clinical results with

  2019-06-28

  

  Based on these preliminary clinical results with low-dose, intermittent zoledronic acid, Hu et al. conducted a randomized phase II clinical study in order to clarify the role of metronomic low-dose zoledronic acid. Sixty breast cancer patients with bone metastases were randomized to receive either 1

• Bone marrow resident Macs Osteomacs are

  2019-06-28

  

  Bone marrow resident Macs (Osteomacs) are located in canopy-like structures in endosteal and periosteal surfaces, above osteoblasts [6]; osteoclasts result from the fusion of several myeloid osteoclast precursors [7]. Osteomacs constitute approximately 17% of the bone marrow Idoxuridine what and th

• In advanced GIST patients where a course

  2019-06-27

  

  In advanced GIST patients where a course of treatment of Imatinib is interrupted by disease progression, subsequent rechallenge with Imatinib restored tumor control in most patients. In the prospective BFR14 trial, 25 patients with disease progression after interruption of one year of treatment rest

• br In Sanguinetti et al and

  2019-06-27

  

  In 1996, Sanguinetti et al. and Barhanin et al. independently found that, when coassembled with the accessory subunit KCNE1, the KCNQ1 and KCNE1 complex could form a channel that very closely exhibited conductive and kinetic properties similar to that of cardiac IKs[14,56]. Kass and coworkers subs

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