• Although the ferromagnetic particles and

  2019-12-30

  

  Although the ferromagnetic particles and T4 Ion Channel Compound Library on the particles were heated by the ac magnetic field, the average temperature of the reaction solution as a whole was kept suitably low for the annealing of DNA ends (16°C). Indeed, no appreciable increase in the temperature

• The absence of the LIG gene in

  2019-12-30

  

  The absence of the LIG3 gene in yeasts has prevented the use of genetically tractable lower eukaryotes, such as Saccharomyces cerevisiae and Schizosaccharomyces pombe, as models to gain insights into the cellular functions of and interplay between the DNA ligases encoded by the LIG1, LIG3 and LIG4 g

• With the recent expanse of technology

  2019-12-30

  

  With the recent expanse of technology to evaluate synthetic lethality, new combinations with DHODH inhibitors may be uncovered (O\'Neil, Bailey, & Hieter, 2017). Many oncogenic backgrounds share synthetic lethality with DHODH. Cells with mutant PTEN have increased glutamine metabolism and are sensit

• Our data indicate that the ability of these promiscuous

  2019-12-29

  

  Our data indicate that the ability of these promiscuous kinases to bind chemically diverse inhibitors is defined by the hydrophobic pocket formed by the activation loop, which is only accessible in the DFG-Asp-out conformation. Inhibitors do not artificially induce the DFG-Asp-out conformation as wa

• For the first time the V carinata transcriptome was

  2019-12-29

  

  For the first time, the V. carinata transcriptome was analyzed and its transcript coding sequences comprehensively characterized. The non-redundant contigs encoding putative CysPs were identified and their focus on  patterns in different tissues were investigated. Our study show that four proteases

• In this study we observed alterations

  2019-12-29

  

  In this study, we observed alterations in mRNA levels of CRF receptors in the PFCx and Hip during the development of sensitization. In particular, in the Hip both CRF receptors showed significantly increased muscarinic receptors when the sensitization condition was established. Similarly, CRF2 recep

• Secondary and primary studies have considered the decision

  2019-12-29

  

  Secondary and primary studies have considered the decision to select the provider and to select components after the component origin is chosen. Examples of secondary and primary studies outside our scope, but still related to decision-making are listed in Tables 1 and 2. The secondary and primary

• Ac-DEVD-AFC DDR expression is upregulated in the glomeruli a

  2019-12-29

  

  DDR1 expression is upregulated in the glomeruli and tubules of injured kidneys [7], [8], [19]; however, what role this receptor plays in kidney resident Ac-DEVD-AFC is unclear. A plausible hypothesis is that DDR1 might contribute to kidney injury by directly exerting a pro-fibrotic action. In favor

• Studies have shown that the cultivation of BMSCs under hypox

  2019-12-29

  

  Studies have shown that the cultivation of BMSCs under hypoxic conditions, treating with cytokines (such as HGF, IGF-1 and IL-6) and viral-mediated CXCR-4 gene delivery have been shown to re-establish CXCR-4 expression on the surface of stem T7 High Yield RNA (Liu et al., 2010, Liu et al., 2014a, Z

• These evidence prompted us to

  2019-12-29

  

  These evidence prompted us to investigate the effectiveness of CT-133, a newly discovered, well-tolerated, selective and potent CRTH2 antagonist, as a treatment of ALI. CT-133 has shown a potential response in treating chronic obstructive pulmonary disease (COPD), allergic rhinitis and CO-1686 austr

• Different types of environmentally induced antinociception

  2019-12-29

  

  Different types of environmentally induced antinociception have been reported in a wide range of species (e.g., Behbehani, 1995, Bolles and Fanselow, 1980, Harris, 1996, Millan, 2002, Rodgers, 1995). According to Bolles and Fanselow (1980), fear and pain are independent and competing motivational sy

• Gambogic Acid Cryoprotectant equilibration and the response

  2019-12-29

  

  Cryoprotectant equilibration and the response to ice concentrated media are the two facets of cellular cryobiological protocols most commonly covered by mathematical modeling. In these models, Gambogic Acid are typically assumed to have uniform, spatially independent extracellular concentrations an

• br Materials and methods br Results br

  2019-12-29

  

  Materials and methods Results Discussion In this study, the N&B analysis showed new evidence regarding the proportion and the oligomerization state of the AT1 and the ETA receptors near or on the plasma membrane. Althought, preliminary studies suggest that the AT1 and the ETA receptors occu

• In the present study we determined concentration response

  2019-12-29

  

  In the present study, we determined concentration–response relationships for selected synthetic progestogens using in vitro luciferase transactivation assays driven by PR, ARα and ARβ from Murray–Darling rainbowfish () and compared the profiles with those obtained from similar assays based on human

• The pathogenesis of formation of an

  2019-12-29

  

  The pathogenesis of formation of an intradural tumor is unclear. Initially, several lines of evidence suggested a neural crest cell of origin for Ewings’s sarcoma based on expression of neuroectodermal markers on tumor Sodium Aescinate [45,46]. However more recently, studies have shown that express

15719 records 911/1048 page Previous Next First page 上5页 911912913914915 下5页 Last page