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br Methods br Results Main characteristics of study populati
2020-10-01

Methods Results Main characteristics of study population are presented in Table 1. AD cases had higher co-morbidity score and lower socioeconomic position than controls. Women with AD had undergone any surgery (unilateral/bilateral oophorectomy, hysterectomy, hysterectomy with bilateral oophor
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Introduction Penetrator with Enhanced Lateral Effect PELE is
2020-10-01

Introduction Penetrator with Enhanced Lateral Effect (PELE) is a kind of ammunition which consists of a low-density material as the filling and a high-density material as the jacket [1,2]. When PELE impact target, the jacket is radially accelerated, expanded and fractured because of distinctive lat
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As with all meta analysis this study certainly has some
2020-09-30

As with all meta-analysis, this study certainly has some limitations. First, our results were derived from unadjusted analyses due to lack of raw data, and lack of further adjusted analyses for age, gender and co-morbidity conditions may impact the reliability of our findings [63]. Second, obvious h
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Thus DGK active sites remain ill defined and
2020-09-29

Thus, DGK-active sites remain ill-defined and, combined with the lack of crystal structures for mammalian DGKs, have limited our understanding of substrate and inhibitor binding. As a result, current DGK inhibitors consist of compounds with poor specificity within the DGK superfamily (de Chaffoy de
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The folate pathway plays an essential role in
2020-09-29

The folate pathway plays an essential role in cell survival by generating 5, 10-methylene tetrahydrofolate as a one-carbon donor for the synthesis of deoxythymidine monophosphate (dTMP), purines, methionine and histidine. Disruption of this pathway leads to the critical deficiency of these key molec
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br Materials and methods br Results and
2020-09-29

Materials and methods Results and discussion Conclusions Clitocypin is another member of the mycocypin family of cysteine protease inhibitors that is unique to selective serotonin reuptake inhibitor shown to exhibit strong insecticidal activity against Colorado potato beetle larvae. This e
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The consistent anti anxiety effects
2020-09-29

The consistent anti-anxiety effects obtained with intra-mPFC injections of CP 376395 strongly suggest a tonic role of CRF at CRF1 receptors located within this limbic NADP/NADPH Quantitation Colorimetric Kit receptor area in the modulation of anxiety in the mouse on the EPM. Intra-mPFC injection of
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We further correlated OPRK and OPRM methylation levels
2020-09-29

We further correlated OPRK1 and OPRM1 methylation levels with individual characteristics in Xinjiang Han and Uygur controls. Partial correlation analyses showed that OPRK1 methylation was positively correlated with age in Uygur male controls (r=0.72, p=0.001, adjusted by body mass index (BMI), gluco
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Pahlavanzadeh and Fakouri Baygi employed PC SAFT EoS to pred
2020-09-29

Pahlavanzadeh and Fakouri-Baygi [6] employed PC-SAFT EoS to predict the ITE of carbon dioxide by aqueous MEA solutions. They used the ideal form of Smith–Missen algorithm to calculate liquid phase concentrations. The results illustrate acceptable accuracies so that the AAD was achieved equal to 36%
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br System description and data collection Fig shows the arra
2020-09-29

System description and data collection Fig. 1 shows the arrangement of the system studied. It provided cooling Fmoc-Ser(tBu)-OH to maintain thermal conditions in an institutional building. The locations of the measured variables (, and ) relating to temperature and flow rate are indicated in Fig
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The Czech Republic is a country with
2020-09-29

The Czech Republic is a country with increasing CDI incidence (1.1 cases per 10,000 patient bed-days in 2008–4.4 cases in 2011–2012 and 6.2 cases per 10,000 patient bed-days in 2012–2013) (Bauer et al., 2011, Davies et al., 2014) and relatively high rates of antibiotic resistant C. difficile strains
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The evaluation of internal exposure in workers with omethoat
2020-09-28

The evaluation of internal exposure in workers with omethoate is challenging. Unfortunately, OPs are metabolized and excreted quickly in the urine usually within 24–48 h of exposure, and the variation in metabolic rates exists. Many factors influence daily urinary output, such as salt intake, urea a
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Role of ROS signaling in regulating cell death pathways
2020-09-28

Role of ROS signaling in regulating cell death pathways has been well established. Involvement of CLIC1 in ROS production has been studied earlier. It was observed that macrophages from clic1 mice showed ~30% decrease in cellular ROS generation which effects macrophage function (Jiang et al., 2012).
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Droxinostat synthesis In the present study we examined wheth
2020-09-28

In the present study we examined whether the gene for estrogen receptor alpha, Esr1, plays a role in the expression of maternal memory in female rats. The approach utilized a newly developed rat Esr1 knockout (KO) rat model (Rumi et al., 2014) to evaluate whether deletion of the Esr1 Droxinostat syn
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The selective estrogen receptor modulators SERMs are another
2020-09-28

The selective estrogen receptor modulators (SERMs) are another type of estrogen receptor ligands. The main difference between SERMs and xenoestrogens relies on the fact that SERMs present functional duality and are able to act both as agonists and antagonists of the estrogen receptors in different t
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